Check out our new article in PLoS Pathogens describing the evolution and persistence of HIV-1 drug resistance in the blood and different tissues. Spoiler alert: the gastrointestinal tract is very different than the blood and lymph nodes!
The title of the study is “A Spatio-Temporal Assessment of Simian/Human Immunodeficiency Virus (SHIV) Evolution Reveals a Highly Dynamic Process within the Host.” It was a wonderful collaboration with Drs. Alison Feder, Dmitri Petrov, Pleuni Pennings, and Shiu-Lok Hu!
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006358
Alison made a cool, short video to explain the study:
Recent Comments