The Ambrose Lab

The Ambrose laboratory studies HIV pathogenesis and therapeutics. We use both molecular and cellular retrovirology methods as well as in vivo models to address important questions about HIV infection and drugs for prevention and treatment.

Our Research Who We Are

About

The Ambrose Lab in the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine studies antiretroviral therapeutics used for HIV-1 prevention and suppression, including understanding virus-host protein interactions that can be exploited as novel drug targets, and the impact of drug resistance on HIV-1 transmission, prevention, and treatment. Recently our studies have expanded to SARS-CoV-2.

Molecular biology

Cellular virology

Animal models

Imaging

Genetics

Projects

The lab conducts multiple molecular and cellular virology projects as well as uses models to research important aspects of HIV infection, disease, and treatment. We also have some SARS-CoV-2 projects. Check it out!