The Ambrose Lab

The Ambrose laboratory studies HIV pathogenesis and therapeutics. We use both molecular and cellular retrovirology methods as well as in vivo models to address important questions about HIV infection and drugs for prevention and treatment.
Our Research Who We Are

About

The Ambrose Lab in the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine studies antiretroviral therapeutics used for HIV-1 prevention and suppression, including understanding virus-host protein interactions that can be exploited as novel drug targets, and the impact of drug resistance on HIV-1 transmission, prevention, and treatment. Recently our studies have expanded to SARS-CoV-2.
Molecular biology
Cellular virology
Animal models
Imaging
Genetics

Projects

The lab conducts multiple molecular and cellular virology projects as well as uses models to research important aspects of HIV infection, disease, and treatment. We also have some SARS-CoV-2 projects. Check it out!

Ambrose Lab News

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University of Pittsburgh PMI Meet & Greet @ ABRCMS 2024
The Phd Program in Microbiology and Immunology (PMI) at the University of Pittsburgh School of Medicine has a booth at…
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Chandra and Zac present at the WCRM
Both Chandra and Zac traveled to Palm Springs, CA for the 28th West Coast Retrovirus Meeting in October. Chandra spoke…
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Congratulations, Jessica!
Jessica recently was awarded a NIH F31 fellowship grant entitled "HIV/Mycobacterium tuberculosis co-infection: cellular dynamics in granulomas." This will fund…
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New HIV Infections in 2023
AIDS Related Deaths in 2023
People Living with HIV in 2023

Our Team

Meet the researchers of the Ambrose Lab!
Zandrea Ambrose, PhD
Zandrea Ambrose, PhD

Principal Investigator

Hardcore retrovirologist

Chandra Nath Roy, PhD
Chandra Nath Roy, PhD

Staff Scientist

Humanized mouse expert

    Hannah Fischer, PhD
    Hannah Fischer, PhD

    Postdoctoral Scholar

    Resident reverse geneticist

      Priya Shanmugapriya, PhD
      Priya Shanmugapriya, PhD

      Postdoctoral Associate

      Newest member of the team

        Zac Ingram, MS
        Zac Ingram, MS

        PhD Student

        HIV capsid guru

          Jessica Medrano
          Jessica Medrano

          MD/PhD Student

          Co-infection immunologist

            Ella Begovic
            Ella Begovic

            MS Student

            Molecular maven

              Meriem Boukaabar
              Meriem Boukaabar

              Undergrad Student

              MIDS Scholar

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